Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration

The sox2 expressing (sox2(+)) progenitors in adult mammalian inner ear lose the capacity to regenerate while progenitors in the zebrafish lateral line are able to proliferate and regenerate damaged HCs throughout lifetime. To mimic the HC damage in mammals, we have established a zebrafish severe inj...

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Vydáno v:eLife
Hlavní autoři: Ye, Zhian, Su, Zhongwu, Xie, Siyu, Liu, Yuye, Wang, Yongqiang, Xu, Xi, Zheng, Yiqing, Zhao, Meng, Jiang, Linjia
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250571/
https://ncbi.nlm.nih.gov/pubmed/32352377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55771
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