Arginine-Modified Polymers Facilitate Poly (Lactide-Co-Glycolide)-Based Nanoparticle Gene Delivery to Primary Human Astrocytes

PURPOSE: Astrocyte dysfunction is a hallmark of central nervous system injury or infection. As a primary contributor to neurodegeneration, astrocytes are an ideal therapeutic target to combat neurodegenerative conditions. Gene therapy has arisen as an innovative technique that provides excellent pro...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Proulx, Jessica, Joshi, Chaitanya, Vijayaraghavalu, Sivakumar, Saraswathy, Manju, Labhasetwar, Vinod, Ghorpade, Anuja, Borgmann, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250304/
https://ncbi.nlm.nih.gov/pubmed/32547019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S250865
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