Reaching for the Stars in the Brain: Polymer-Mediated Gene Delivery to Human Astrocytes

Astrocytes, the “star-shaped” glial cells, are appealing gene-delivery targets to treat neurological diseases due to their diverse roles in brain homeostasis and disease. Cationic polymers have successfully delivered genes to mammalian cells and hence present a viable, non-immunogenic alternative to...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Joshi, Chaitanya R., Raghavan, Vijay, Vijayaraghavalu, Sivakumar, Gao, Yue, Saraswathy, Manju, Labhasetwar, Vinod, Ghorpade, Anuja
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082920/
https://ncbi.nlm.nih.gov/pubmed/30081235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.06.009
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