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Blood vitronectin induces detrimental brain IL-6 and correlates with outcomes after stroke only in female mice

BACKGROUND AND PURPOSE: Women have worse stroke outcomes than men, especially after menopause. Few studies have focused on female-specific mechanisms, other than hormones. We investigated the role of the blood protein vitronectin after ischemic stroke in mice. METHODS: Adult male and female vitronec...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Jia, Cuihong, Malone, Hannah M., Keasey, Matthew P., Lovins, Chiharu, Elam, Jacob, Hagg, Theo
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249257/
https://ncbi.nlm.nih.gov/pubmed/32312218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.120.029036
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