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Inhibition of astrocyte FAK-JNK signaling promotes subventricular zone neurogenesis through CNTF
Astrocyte-derived ciliary neurotrophic factor (CNTF) promotes adult subventricular zone (SVZ) neurogenesis. We found that focal adhesion kinase (FAK) and JNK, but not ERK or P38, repress CNTF in vitro. Here, we defined the FAK-JNK pathway and its regulation of CNTF in mice, and the related leukemia...
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| Publicado en: | Glia |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6863602/ https://ncbi.nlm.nih.gov/pubmed/30500112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23498 |
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