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Inhibition of astrocyte FAK-JNK signaling promotes subventricular zone neurogenesis through CNTF
Astrocyte-derived ciliary neurotrophic factor (CNTF) promotes adult subventricular zone (SVZ) neurogenesis. We found that focal adhesion kinase (FAK) and JNK, but not ERK or P38, repress CNTF in vitro. Here, we defined the FAK-JNK pathway and its regulation of CNTF in mice, and the related leukemia...
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| Publicado no: | Glia |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6863602/ https://ncbi.nlm.nih.gov/pubmed/30500112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23498 |
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