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Mechanistic Understanding of Peptide Analogues, DALDA, [Dmt(1)]DALDA, and KGOP01, Binding to the Mu Opioid Receptor

The mu opioid receptor (MOR) is the primary target for analgesia of endogenous opioid peptides, alkaloids, synthetic small molecules with diverse scaffolds, and peptidomimetics. Peptide-based opioids are viewed as potential analgesics with reduced side effects and have received constant scientific i...

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Publicat a:Molecules
Autors principals: Dumitrascuta, Maria, Bermudez, Marcel, Ballet, Steven, Wolber, Gerhard, Spetea, Mariana
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248707/
https://ncbi.nlm.nih.gov/pubmed/32365707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25092087
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