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Cyclic Dinucleotides at the Forefront of Innate Immunity

Cyclic dinucleotides (CDNs) have emerged as ubiquitous signaling molecules in all domains of life. In eukaryotes, CDN signaling systems are evolutionarily ancient and have developed to sense and respond to pathogen infection. On the other hand, dysregulation of these pathways has been implicated in...

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Publicado en:Curr Opin Cell Biol
Autores principales: Zaver, Shivam A., Woodward, Joshua J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247925/
https://ncbi.nlm.nih.gov/pubmed/31958669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2019.12.004
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