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Cyclic Dinucleotides at the Forefront of Innate Immunity

Cyclic dinucleotides (CDNs) have emerged as ubiquitous signaling molecules in all domains of life. In eukaryotes, CDN signaling systems are evolutionarily ancient and have developed to sense and respond to pathogen infection. On the other hand, dysregulation of these pathways has been implicated in...

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Bibliographic Details
Published in:Curr Opin Cell Biol
Main Authors: Zaver, Shivam A., Woodward, Joshua J.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247925/
https://ncbi.nlm.nih.gov/pubmed/31958669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2019.12.004
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