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The secreted protein DEL-1 activates a β3 integrin–FAK–ERK1/2–RUNX2 pathway and promotes osteogenic differentiation and bone regeneration

The integrin-binding secreted protein developmental endothelial locus-1 (DEL-1) is involved in the regulation of both the initiation and resolution of inflammation in different diseases, including periodontitis, an oral disorder characterized by inflammatory bone loss. Here, using a mouse model of b...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Yuh, Da-Yo, Maekawa, Tomoki, Li, Xiaofei, Kajikawa, Tetsuhiro, Bdeir, Khalil, Chavakis, Triantafyllos, Hajishengallis, George
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247308/
https://ncbi.nlm.nih.gov/pubmed/32280065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013024
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