Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis

β2-integrins promote neutrophil recruitment to infected tissues and are crucial for host defense. Neutrophil recruitment is defective in leukocyte adhesion deficiency type-1 (LAD1), a condition caused by mutations in the CD18 (β2-integrin) gene. Using a model of Citrobacter rodentium (CR)-induced co...

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Publicado no:Cell Rep
Main Authors: Wang, Baomei, Lim, Jong-Hyung, Kajikawa, Tetsuhiro, Li, Xiaofei, Vallance, Bruce A., Moutsopoulos, Niki M., Chavakis, Triantafyllos, Hajishengallis, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404229/
https://ncbi.nlm.nih.gov/pubmed/30726742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.01.054
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