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Modulating functional amyloid formation via alternative splicing of the premelanosomal protein PMEL17
The premelanosomal protein (PMEL17) forms functional amyloid fibrils involved in melanin biosynthesis. Multiple PMEL17 isoforms are produced, two of which arise from excision of a cryptic intron within the amyloid-forming repeat (RPT) domain, leading to long (lRPT) and short (sRPT) isoforms with 10...
Shranjeno v:
| izdano v: | J Biol Chem |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247297/ https://ncbi.nlm.nih.gov/pubmed/32277052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013012 |
| Oznake: |
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