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Pmel17 Initiates Premelanosome Morphogenesis within Multivesicular Bodies

Melanosomes are tissue-specific organelles within which melanin is synthesized and stored. The melanocyte-specific glycoprotein Pmel17 is enriched in the lumen of premelanosomes, where it associates with characteristic striations of unknown composition upon which melanin is deposited. However, Pmel1...

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Bibliographic Details
Main Authors: Berson, Joanne F., Harper, Dawn C., Tenza, Danielle, Raposo, Graça, Marks, Michael S.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC60267/
https://ncbi.nlm.nih.gov/pubmed/11694580
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