Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins

The ancient paralogs premelanosome protein (<i>PMEL</i>) and glycoprotein nonmetastatic melanoma protein B (<i>GPNMB</i>) have independently emerged as intriguing disease loci in recent years. Both proteins possess common functional domains and variants that cause a shared spectrum of overlapping ph...

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Manylion Llyfryddiaeth

Prif Awduron:	Paul W. Chrystal, Tim Footz, Elizabeth D. Hodges, Justin A. Jensen, Michael A. Walter, W. Ted Allison
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2021-06-01
Cyfres:	Molecules
Pynciau:	PKAT family proteins PMEL-17-related family PTHR11861 functional amyloid melanosomes pigmentation neurodegeneration
Mynediad Ar-lein:	https://www.mdpi.com/1420-3049/26/12/3529
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!