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Pharmacological Inhibition of Cyclin-Dependent Kinases Triggers Anti-Fibrotic Effects in Hepatic Stellate Cells In Vitro

Liver fibrosis is a wound healing process in response to chronic liver injury, which is characterized by the accumulation of extracellular collagen produced by Hepatic Stellate Cells (HSCs). This process involves cell cycle re-entry and proliferation of normally quiescent HSCs controlled by cyclins...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hübbers, Anna, Hennings, Julia, Lambertz, Daniela, Haas, Ute, Trautwein, Christian, Nevzorova, Yulia A., Sonntag, Roland, Liedtke, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246535/
https://ncbi.nlm.nih.gov/pubmed/32380742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093267
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