Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice

Liver fibrogenesis is associated with the transition of quiescent hepatocytes and hepatic stellate cells (HSC) into the cell cycle. Exit from quiescence is controlled by E-type cyclins (CcnE1, CcnE2). Thus, the aim of the current study was to investigate the contribution of E-type cyclins for liver...

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Hauptverfasser: Nevzorova, Yulia A., Bangen, Jörg-Martin, Hu, Wei, Haas, Ute, Weiskirchen, Ralf, Gassler, Nikolaus, Huss, Sebastian, Tacke, Frank, Sicinski, Piotr, Trautwein, Christian, Liedtke, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396430/
https://ncbi.nlm.nih.gov/pubmed/22454377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25736
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