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Data-based RNA-seq simulations by binomial thinning

BACKGROUND: With the explosion in the number of methods designed to analyze bulk and single-cell RNA-seq data, there is a growing need for approaches that assess and compare these methods. The usual technique is to compare methods on data simulated according to some theoretical model. However, as re...

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Publié dans:BMC Bioinformatics
Auteur principal: Gerard, David
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245910/
https://ncbi.nlm.nih.gov/pubmed/32448189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3450-9
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