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Statistical inference for time course RNA-Seq data using a negative binomial mixed-effect model
BACKGROUND: Accurate identification of differentially expressed (DE) genes in time course RNA-Seq data is crucial for understanding the dynamics of transcriptional regulatory network. However, most of the available methods treat gene expressions at different time points as replicates and test the si...
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| Publicado no: | BMC Bioinformatics |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5002174/ https://ncbi.nlm.nih.gov/pubmed/27565575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1180-9 |
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