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Data-based RNA-seq simulations by binomial thinning

Abstract Background With the explosion in the number of methods designed to analyze bulk and single-cell RNA-seq data, there is a growing need for approaches that assess and compare these methods. The usual technique is to compare methods on data simulated according to some theoretical model. Howeve...

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Autor principal: David Gerard
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2020-05-01
Colección:BMC Bioinformatics
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Acceso en línea:http://link.springer.com/article/10.1186/s12859-020-3450-9
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