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Circadian clock control of eIF2α phosphorylation is necessary for rhythmic translation initiation

The circadian clock in eukaryotes controls transcriptional and posttranscriptional events, including regulation of the levels and phosphorylation state of translation factors. However, the mechanisms underlying clock control of translation initiation, and the impact of this potential regulation on r...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Karki, Shanta, Castillo, Kathrina, Ding, Zhaolan, Kerr, Olivia, Lamb, Teresa M., Wu, Cheng, Sachs, Matthew S., Bell-Pedersen, Deborah
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245112/
https://ncbi.nlm.nih.gov/pubmed/32355000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918459117
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