Positive epistasis between viral polymerase and the 3′ untranslated region of its genome reveals the epidemiologic fitness of dengue virus

Dengue virus (DENV) is a global health threat, causing repeated epidemics throughout the tropical world. While low herd immunity levels to any one of the four antigenic types of DENV predispose populations to outbreaks, viral genetic determinants that confer greater fitness for epidemic spread is an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Syenina, Ayesa, Vijaykrishna, Dhanasekaran, Gan, Esther Shuyi, Tan, Hwee Cheng, Choy, Milly M., Siriphanitchakorn, Tanamas, Cheng, Colin, Vasudevan, Subhash G., Ooi, Eng Eong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2020
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245076/
https://ncbi.nlm.nih.gov/pubmed/32366663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1919287117
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