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Discovery of N-(2-(Benzylamino)-2-oxoethyl)benzamide analogs as a Novel Scaffold of Pancreatic β-cell Protective Agents against ER Stress

Endoplasmic reticulum (ER) stress-induced Pancreatic β-cell dysfunction and death plays important roles in the development of diabetes. The 1,2,3-triazole derivative 1 is one of only a few structures that have thus far been identified that protect β cells against ER stress. However, this compound ha...

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Vydáno v:Chem Biol Drug Des
Hlavní autoři: Eeda, Venkateswararao, Herlea-Pana, Oana, Lim, Hui-Ying, Wang, Weidong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245055/
https://ncbi.nlm.nih.gov/pubmed/31755655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13650
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