A novel CNS-homing peptide for targeting neuroinflammatory lesions in experimental autoimmune encephalomyelitis

Using phage peptide library screening, we identified peptide-encoding phages that selectively home to the inflamed central nervous system (CNS) of mice with experimental autoimmune encephalomyelitis (EAE), a model of human multiple sclerosis (MS). A phage peptide display library encoding cyclic 9-am...

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Udgivet i:Mol Cell Probes
Main Authors: Acharya, Bodhraj, Meka, Rakeshchandra R., Venkatesha, Shivaprasad H., Lees, Jason, Teesalu, Tambet, Moudgil, Kamal D.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245014/
https://ncbi.nlm.nih.gov/pubmed/32035108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcp.2020.101530
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