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Celastrol suppresses experimental autoimmune encephalomyelitis via MAPK/ SGK1-regulated mediators of autoimmune pathology

OBJECTIVE AND DESIGN: Multiple sclerosis (MS) is a debilitating autoimmune disease involving immune dysregulation of the pathogenic T helper 17 (Th17) versus protective T regulatory (Treg) cell subsets, besides other cellular aberrations. Studies on the mechanisms underlying these changes have unrav...

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Publicat a:Inflamm Res
Autors principals: Venkatesha, Shivaprasad H., Moudgil, Kamal D.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517245/
https://ncbi.nlm.nih.gov/pubmed/30820608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-019-01219-x
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