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IL-27-induced modulation of autoimmunity and its therapeutic potential
Interleukin-27 (IL-27) is a new member of the IL-12 family. It is produced by activated antigen-presenting cells and plays an important role in the regulation of CD4+ T cell differentiation and immune response. IL-27 activates multiple signaling cascades, including the JAK-STAT and p38 MAPK pathways...
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| Publicado no: | Autoimmun Rev |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628569/ https://ncbi.nlm.nih.gov/pubmed/26253381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autrev.2015.08.001 |
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