Klotho Alleviates Lung Injury Caused by Paraquat via Suppressing ROS/P38 MAPK-Regulated Inflammatory Responses and Apoptosis

Acute lung injury (ALI) induced by paraquat (PQ) progresses rapidly with high mortality; however, there is no effective treatment, and the specific mechanism is not well understood. The antiaging protein klotho (KL) has multiple functions and exerts significant influences on various pathophysiologic...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Zhang, Zhiqiang, Nian, Qing, Chen, Gang, Cui, Shuqing, Han, Yuzhen, Zhang, Jinying
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244968/
https://ncbi.nlm.nih.gov/pubmed/32509139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/1854206
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