Vaccarin prevents ox-LDL-induced HUVEC EndMT, inflammation and apoptosis by suppressing ROS/p38 MAPK signaling

Oxidized low-density lipoprotein (ox-LDL)-induced endothelial-mesenchymal transition (EndMT), inflammation and apoptosis in endothelial cells play crucial roles in the progression of cardiovascular diseases including atherosclerosis. Vaccarin is a flavonoid glycoside from vaccariae semen associated...

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Pubblicato in:Am J Transl Res
Autori principali: Gong, Leilei, Lei, Yueyue, Liu, Yixiao, Tan, Fanggen, Li, Shuangshuang, Wang, Xinyue, Xu, Manlin, Cai, Weiwei, Du, Bin, Xu, Fei, Zhou, Yuetao, Han, Hongxiu, Sun, Haijian, Qiu, Liying
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511755/
https://ncbi.nlm.nih.gov/pubmed/31105824
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