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Methylation of a CGATA element inhibits binding and regulation by GATA-1
Alterations in DNA methylation occur during development, but the mechanisms by which they influence gene expression remain uncertain. There are few examples where modification of a single CpG dinucleotide directly affects transcription factor binding and regulation of a target gene in vivo. Here, we...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244756/ https://ncbi.nlm.nih.gov/pubmed/32444652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16388-1 |
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