A Cell-based Screen in Actinomyces oris to Identify Sortase Inhibitors

Sortase enzymes are attractive antivirulence drug targets that attach virulence factors to the surface of Staphylococcus aureus and other medically significant bacterial pathogens. Prior efforts to discover a useful sortase inhibitor have relied upon an in vitro activity assay in which the enzyme is...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Gosschalk, Jason E., Chang, Chungyu, Sue, Christopher K., Siegel, Sara D., Wu, Chenggang, Kattke, Michele D., Yi, Sung Wook, Damoiseaux, Robert, Jung, Michael E., Ton-That, Hung, Clubb, Robert T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244523/
https://ncbi.nlm.nih.gov/pubmed/32444661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65256-x
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