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A Cell-based Screen in Actinomyces oris to Identify Sortase Inhibitors
Sortase enzymes are attractive antivirulence drug targets that attach virulence factors to the surface of Staphylococcus aureus and other medically significant bacterial pathogens. Prior efforts to discover a useful sortase inhibitor have relied upon an in vitro activity assay in which the enzyme is...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244523/ https://ncbi.nlm.nih.gov/pubmed/32444661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65256-x |
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