Osteogenesis imperfecta mutations in plastin 3 lead to impaired calcium regulation of actin bundling

Mutations in actin-bundling protein plastin 3 (PLS3) emerged as a cause of congenital osteoporosis, but neither the role of PLS3 in bone development nor the mechanisms underlying PLS3-dependent osteoporosis are understood. Of the over 20 identified osteoporosis-linked PLS3 mutations, we investigated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Bone Res
Main Authors: Schwebach, Christopher L., Kudryashova, Elena, Zheng, Weili, Orchard, Matthew, Smith, Harper, Runyan, Lucas A., Egelman, Edward H., Kudryashov, Dmitri S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244493/
https://ncbi.nlm.nih.gov/pubmed/32509377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-020-0095-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados