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The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling

L-plastin is a calcium-regulated actin-bundling protein that is expressed in cells of hematopoietic origin and in most metastatic cancer cells. These cell types are mobile and require the constant remodeling of their actin cytoskeleton, where L-plastin bundles filamentous actin. The calcium-dependen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ishida, Hiroaki, Jensen, Katharine V., Woodman, Andrew G., Hyndman, M. Eric, Vogel, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286426/
https://ncbi.nlm.nih.gov/pubmed/28145401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40662
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