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Osteogenesis imperfecta mutations in plastin 3 lead to impaired calcium regulation of actin bundling
Mutations in actin-bundling protein plastin 3 (PLS3) emerged as a cause of congenital osteoporosis, but neither the role of PLS3 in bone development nor the mechanisms underlying PLS3-dependent osteoporosis are understood. Of the over 20 identified osteoporosis-linked PLS3 mutations, we investigated...
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| Publicat a: | Bone Res |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244493/ https://ncbi.nlm.nih.gov/pubmed/32509377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-020-0095-2 |
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