Carregant...
Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance
CRISPR-Cas9 genome engineering has revolutionised high-throughput functional genomic screens. However, recent work has raised concerns regarding the performance of CRISPR-Cas9 screens using TP53 wild-type human cells due to a p53-mediated DNA damage response (DDR) limiting the efficiency of generati...
Guardat en:
| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2020
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244323/ https://ncbi.nlm.nih.gov/pubmed/32441252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55325 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|