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Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy
Interpreting how multicellular interactions in the tumor affect resistance pathways to BRAF and MEK1/2 MAPK inhibitors (MAPKi) remains a challenge. To investigate this, we profiled global ligand-receptor interactions among tumor and stromal/immune cells from biopsies of MAPK-driven disease. MAPKi in...
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| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244320/ https://ncbi.nlm.nih.gov/pubmed/32494745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz8521 |
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