Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary

In mammals, the timing of meiosis entry is regulated by signals from the gonadal environment. All-trans retinoic acid (ATRA) signaling is considered the key pathway that promotes Stra8 (stimulated by retinoic acid 8) expression and, in turn, meiosis entry. This model, however, is debated because it...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Chassot, Anne-Amandine, Le Rolle, Morgane, Jolivet, Geneviève, Stevant, Isabelle, Guigonis, Jean-Marie, Da Silva, Fabio, Nef, Serge, Pailhoux, Eric, Schedl, Andreas, Ghyselinck, Norbert B., Chaboissier, Marie-Christine
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244317/
https://ncbi.nlm.nih.gov/pubmed/32494737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz1261
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