Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary

In mammals, the timing of meiosis entry is regulated by signals from the gonadal environment. All-trans retinoic acid (ATRA) signaling is considered the key pathway that promotes Stra8 (stimulated by retinoic acid 8) expression and, in turn, meiosis entry. This model, however, is debated because it...

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Опубликовано в: :Sci Adv
Главные авторы: Chassot, Anne-Amandine, Le Rolle, Morgane, Jolivet, Geneviève, Stevant, Isabelle, Guigonis, Jean-Marie, Da Silva, Fabio, Nef, Serge, Pailhoux, Eric, Schedl, Andreas, Ghyselinck, Norbert B., Chaboissier, Marie-Christine
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for the Advancement of Science 2020
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244317/
https://ncbi.nlm.nih.gov/pubmed/32494737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz1261
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