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ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

Substantial evidence exists that during fetal ovarian development in mammals, retinoic acid (RA) induces germ cells to express the pre-meiotic marker Stra8 and enter meiosis, and that these effects are prevented in the fetal testis by the RA-degrading P450 enzyme CYP26B1. Nonetheless, the role of RA...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bowles, Josephine, Feng, Chun-Wei, Miles, Kim, Ineson, Jessica, Spiller, Cassy, Koopman, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762892/
https://ncbi.nlm.nih.gov/pubmed/26892828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10845
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