Exploring the Molecular Basis for Substrate Affinity and Structural Stability in Bacterial GH39 β-Xylosidases

The glycoside hydrolase family 39 (GH39) is a functionally expanding family with limited understanding about the molecular basis for substrate specificity and extremophilicity. In this work, we demonstrate the key role of the positive-subsite region in modulating substrate affinity and how the lack...

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Dettagli Bibliografici
Pubblicato in:Front Bioeng Biotechnol
Autori principali: de Morais, Mariana Abrahão Bueno, Polo, Carla Cristina, Domingues, Mariane Noronha, Persinoti, Gabriela Felix, Pirolla, Renan Augusto Siqueira, de Souza, Flávio Henrique Moreira, Correa, Jessica Batista de Lima, dos Santos, Camila Ramos, Murakami, Mário Tyago
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Bioengineering and Biotechnology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242879/
https://ncbi.nlm.nih.gov/pubmed/32500063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00419
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