Exploring the Molecular Basis for Substrate Affinity and Structural Stability in Bacterial GH39 β-Xylosidases

The glycoside hydrolase family 39 (GH39) is a functionally expanding family with limited understanding about the molecular basis for substrate specificity and extremophilicity. In this work, we demonstrate the key role of the positive-subsite region in modulating substrate affinity and how the lack...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: de Morais, Mariana Abrahão Bueno, Polo, Carla Cristina, Domingues, Mariane Noronha, Persinoti, Gabriela Felix, Pirolla, Renan Augusto Siqueira, de Souza, Flávio Henrique Moreira, Correa, Jessica Batista de Lima, dos Santos, Camila Ramos, Murakami, Mário Tyago
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242879/
https://ncbi.nlm.nih.gov/pubmed/32500063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00419
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