Hippocampal Synaptic Dysfunction in a Mouse Model of Huntington Disease Is Not Alleviated by Ceftriaxone Treatment

Glutamate transporters, particularly glutamate transporter 1 (GLT-1), help to prevent the adverse effects associated with glutamate toxicity by rapidly clearing glutamate from the extracellular space. Since GLT-1 expression and/or function are reduced in many neurodegenerative diseases, upregulation...

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Pubblicato in:eNeuro
Autori principali: Wilkie, Crystal M., Barnes, Jocelyn R., Benson, Cherry-Lynn M., Brymer, Kyle J., Nafar, Firoozeh, Parsons, Matthew P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2020
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Research Article: New Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242817/
https://ncbi.nlm.nih.gov/pubmed/32354757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0440-19.2020
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