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Stability and Activity of the Hyperglycosylated Human Interferon-β R27T Variant

A hyperglycosylated recombinant human interferon-β (rhIFN-β) R27T mutant was established to improve relapsing-remitting multiple sclerosis (RRMS) in our previous study. We focused on the stability of the R27T mutant throughout its production lifetime, including culture, purification, and storage bef...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Song, Kyoung, Moon, Dae Bong, Kim, Na Young, Shin, Young Kee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242330/
https://ncbi.nlm.nih.gov/pubmed/32439982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65495-y
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