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Understanding Concomitant Physical and Chemical Transformations of Simvastatin During Dry Ball Milling
The present study investigates concomitant processes of solid-state disordering and oxidation of simvastatin during milling. The separate dry ball milling of crystalline and amorphous powders of simvastatin were conducted at ambient temperature for 10 and 60 min each. The relative crystallinity was...
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| 出版年: | AAPS PharmSciTech |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer International Publishing
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7242262/ https://ncbi.nlm.nih.gov/pubmed/32440782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-020-01687-z |
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