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Update on Hsp90 Inhibitors in Clinical Trial
Twenty-five years ago the first small molecule inhibitors of Hsp90 were identified. In the intervening years there has been dramatic progress in basic scientific understanding of the Hsp90 chaperone machinery and in the role of Hsp90 in malignancy. The first-in-class Hsp90 inhibitor 17-AAG entered i...
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| Publicat a: | Curr Top Med Chem |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7241864/ https://ncbi.nlm.nih.gov/pubmed/19860730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/156802609789895728 |
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