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THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation

Lipoprotein lipase (LPL) is upregulated in atherosclerotic lesions and it may promote the progression of atherosclerosis, but the mechanisms behind this process are not completely understood. We previously showed that the phosphorylation of Akt within THP-1 macrophages is increased in response to th...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Marshall, Jenika D., Courage, Emily R., Elliott, Ryan F., Fitzpatrick, Madeline N., Kim, Anne D., Lopez-Clavijo, Andrea F., Woolfrey, Bronwyn A., Ouimet, Mireille, Wakelam, Michael J. O., Brown, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241781/
https://ncbi.nlm.nih.gov/pubmed/32437392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233180
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