Efficacy and safety of lower dose tenofovir disoproxil fumarate and efavirenz versus standard dose in HIV-infected, antiretroviral-naive adults: a multicentre, randomized, noninferiority trial

Reduced doses of antiretroviral (ARV) drugs may lower toxicity while preserving efficacy. We aimed to evaluate the efficacy of reduced doses of both tenofovir disoproxil fumarate (TDF) and efavirenz for the treatment of HIV-1 infection. In this open-label, non-inferiority trial, HIV-1-infected antir...

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Bibliografiska uppgifter
I publikationen:Emerg Microbes Infect
Huvudupphovsmän: Chen, Jun, Chen, Rong, Shen, Yinzhong, Wei, Hongxia, Wang, Xicheng, Zhang, Renfang, Hu, Zhiliang, Xie, Ronghui, Huang, Qiong, Wang, Jiangrong, Liu, Li, Qi, Tangkai, Wang, Zhenyan, Song, Wei, Tang, Yang, Sun, Jianjun, Lu, Hongzhou
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2020
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241516/
https://ncbi.nlm.nih.gov/pubmed/32267205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2020.1752609
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