Efficacy and safety of lower dose tenofovir disoproxil fumarate and efavirenz versus standard dose in HIV-infected, antiretroviral-naive adults: a multicentre, randomized, noninferiority trial

Reduced doses of antiretroviral (ARV) drugs may lower toxicity while preserving efficacy. We aimed to evaluate the efficacy of reduced doses of both tenofovir disoproxil fumarate (TDF) and efavirenz for the treatment of HIV-1 infection. In this open-label, non-inferiority trial, HIV-1-infected antir...

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Publicado en:Emerg Microbes Infect
Main Authors: Chen, Jun, Chen, Rong, Shen, Yinzhong, Wei, Hongxia, Wang, Xicheng, Zhang, Renfang, Hu, Zhiliang, Xie, Ronghui, Huang, Qiong, Wang, Jiangrong, Liu, Li, Qi, Tangkai, Wang, Zhenyan, Song, Wei, Tang, Yang, Sun, Jianjun, Lu, Hongzhou
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2020
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241516/
https://ncbi.nlm.nih.gov/pubmed/32267205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2020.1752609
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