Glycyrrhetinic Acid-Induced MiR-663a Alleviates Hepatic Stellate Cell Activation by Attenuating the TGF-β/Smad Signaling Pathway

Glycyrrhetinic acid (GA), a hydrolysate of glycyrrhizic acid from licorice root extract, has been used to treat liver fibrotic diseases. However, the molecular mechanism involved in the antifibrotic effects of GA remains unclear. The involvement of miR-663a and its roles in TGF-β-1-induced hepatic s...

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Vydáno v:Evid Based Complement Alternat Med
Hlavní autoři: Guo, Xin-Xin, Yang, Wen-Na, Dong, Ben-Sheng, Shang, Jia-Wei, Su, Shi-Bing, Yan, Xiu-Li, Zhang, Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240796/
https://ncbi.nlm.nih.gov/pubmed/32454854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3156267
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