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Glycyrrhetinic Acid-Induced MiR-663a Alleviates Hepatic Stellate Cell Activation by Attenuating the TGF-β/Smad Signaling Pathway

Glycyrrhetinic acid (GA), a hydrolysate of glycyrrhizic acid from licorice root extract, has been used to treat liver fibrotic diseases. However, the molecular mechanism involved in the antifibrotic effects of GA remains unclear. The involvement of miR-663a and its roles in TGF-β-1-induced hepatic s...

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Dades bibliogràfiques
Publicat a:Evid Based Complement Alternat Med
Autors principals: Guo, Xin-Xin, Yang, Wen-Na, Dong, Ben-Sheng, Shang, Jia-Wei, Su, Shi-Bing, Yan, Xiu-Li, Zhang, Hui
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240796/
https://ncbi.nlm.nih.gov/pubmed/32454854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3156267
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