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Glycyrrhetinic Acid-Induced MiR-663a Alleviates Hepatic Stellate Cell Activation by Attenuating the TGF-β/Smad Signaling Pathway

Glycyrrhetinic acid (GA), a hydrolysate of glycyrrhizic acid from licorice root extract, has been used to treat liver fibrotic diseases. However, the molecular mechanism involved in the antifibrotic effects of GA remains unclear. The involvement of miR-663a and its roles in TGF-β-1-induced hepatic s...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Guo, Xin-Xin, Yang, Wen-Na, Dong, Ben-Sheng, Shang, Jia-Wei, Su, Shi-Bing, Yan, Xiu-Li, Zhang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240796/
https://ncbi.nlm.nih.gov/pubmed/32454854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3156267
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