Inhibitory effects of oxymatrine on hepatic stellate cells activation through TGF-β/miR-195/Smad signaling pathway

BACKGROUND: Oxymatrine (OM), a quinolizidine alkaloid extracted from a herb Sophorae Flavescentis Radix, has been used to treat liver fibrotic diseases. However, the mechanism of its anti-fibrosis effects is still unclear. TGF-β/Smad signaling and miR-195 have been proved to paly an important role i...

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Publicado en:BMC Complement Altern Med
Autores principales: Song, Li-Ying, Ma, Yu-Tao, Fang, Wei-Jin, He, Yang, Wu, Jia-Li, Zuo, Shan-Ru, Deng, Zhen-Zhen, Wang, Sheng-Feng, Liu, Shi-Kun
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585021/
https://ncbi.nlm.nih.gov/pubmed/31221141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-019-2560-2
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