ALKBH4 Functions as a Suppressor of Colorectal Cancer Metastasis via Competitively Binding to WDR5

BACKGROUND: Epithelial-Mesenchymal Transition (EMT) is a major process in the initiation of tumor metastasis, where cancer cells lose sessile epithelial potential and gain mesenchymal phenotype. Large-scale cell identity shifts are often orchestrated on an epigenetic level and the interplay between...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Shen, Chaoqin, Yan, Tingting, Tong, Tianying, Shi, Debin, Ren, Linlin, Zhang, Youwei, Zhang, Xinyu, Cao, Yingying, Yan, Yuqing, Ma, Yanru, Zhu, Xiaoqiang, Tian, Xianglong, Fang, Jing-Yuan, Chen, Haoyan, Ji, Linhua, Hong, Jie, Xuan, Baoqin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240015/
https://ncbi.nlm.nih.gov/pubmed/32478065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00293
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