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Histone H3K27M Mutation Overrides Histological Grading in Pediatric Gliomas
Pediatric high-grade gliomas (HGG) are rare aggressive tumors that present a prognostic and therapeutic challenge. Diffuse midline glioma, H3K27M–mutant is a new entity introduced to HGG in the latest WHO classification. In this study we evaluated the presence of H3K27M mutation in 105 tumor samples...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7239884/ https://ncbi.nlm.nih.gov/pubmed/32433577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65272-x |
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